Varijashree was widely recognised as a child prodigy who could identify 100 Carnatic ragas at the tender age of 18 months, who began performing Carnatic concerts at the age of 4. She initially trained under her musician parents Vidwan H S Venugopal and Vidhushi T V Rama, Vidhishi H Geetha, Vidhushi Vasantha Srinivasan, Vidwan D S Srivatsa, and later under Ganakalanidhi Vidwan Salem P Sundaresan. 

Coming from a rich background of an intricate classical form of music such as Carnatic music, Varijashree is one of the pioneering artists in applying the techniques, fundamentals, and the sound & soul of Indian singing in the global music context. 

​

Apart from being a singer, Varijashree is also a flautist, composer, a song writer, and a music educator.

Her unique capabilities of using her voice as an instrument and the blending of her singing with various music cultures using the Indian singing techniques, has led her to being featured alongside and collaborating with few of the most notable musical personalities in the world such as Bobby McFerrin, Michael League (Snarky Puppy), Victor Wooten, Bèla Fleck, Hamilton de Holanda, Eddie Gomez, C4 trio, Trio Bobo, Anat Cohen, Jacob Collier, Sandeep Chowta, Praveen D Rao, Ricky Kej, EYM trio, and more.